Fred Hutch

Happy #Obliteride weekend! We had a blast kicking off year 13 of #fredhutch Obliteride tonight, an event that brings together a global community with one goal: fueling lifesaving cancer research! See ya tomorrow at the start line, Obliteriders! 🚴♀️🏃

Mutations in the nearly 2,100 genes that encode RNA-associated proteins occur in cancer, neurodegeneration, developmental disorders and other diseases. But it’s been difficult to pin down what each of those proteins is doing within the cell. Researchers at Fred Hutch invented a new screening method called ReLiC — described recently in the journal Nature Methods — that solves that problem using CRISPR-Cas9, the Nobel-prize winning gene-editing technology. “This approach has opened up a new way for us to systematically interrogate RNA regulation,” said Arvind (Rasi) Subramaniam, PhD, a researcher in the Basic Sciences Division who studies how cells make proteins from RNA. Read more: https://xmrrwallet.com/cmx.pbit.ly/4lecXTu

In the center of the Fred Hutch South Lake Union campus stands a towering 60-foot sculpture. It may seem a contradiction, but the landmark architectural sculpture should strike observers as both monumental and delicate. That's according to its creator, architectural sculptor Ed Carpenter. Carpenter characterizes "Vessel" as a centerpiece for Fred HUtch. "My intention was to create a sculpture that could not be anywhere else - that would feel right for this site and this institution both physically and metaphorically," he said. Read more: https://xmrrwallet.com/cmx.pbit.ly/3UhLCor #FH50

Looking to reduce your risk for #colorectalcancer? Focus on fiber-rich whole foods, says Dr. Heather Greenlee, an epidemiologist at Fred Hutch and director of the Fred Hutch-based Cook for Your Life. Aim for about 30 grams of fiber per day. https://xmrrwallet.com/cmx.pnyti.ms/3GYEZo5

Meet Jimena Perez Tetuan, an intern in our Summer Undergraduate Research Program! Currently an undergrad studying bioengineering and biochemistry at Northeastern University in Boston, Jimena is spending her summer in the lab of Dr. James Alvarez studying breast tumor recurrence, learning new lab techniques and getting hands-on experience in cancer biology. Learn more about the Summer Undergraduate Research Program at Fred Hutch: https://xmrrwallet.com/cmx.pbit.ly/45ht7FM

We’d like to thank our #Obliteride sponsors for their incredible support. Thank you to The Sloan Foundation, University Village Shopping Center, Edward Jones, Sinegal Family Foundation, Boulder Associates, GLY Construction, Lamar Advertising of Seattle-Tacoma, Pfizer, The Sahsen Fund, Silver Cloud Inns & Hotels, Alexandria Real Estate Equities, Inc., Bank of America, Freestone Capital Management, Microsoft, Nordstrom, SanMar, and TerraPower. Let’s continue to fuel life-changing research together!

Ten Washington state organizations received up to $15,000 each from Fred Hutch’s Community Grants Program to support the health needs of underserved communities across the state. This year brought a surge in applications, reflecting growing need and community-driven innovation. Read more: https://xmrrwallet.com/cmx.pbit.ly/4fkKhH1

When most people think of cancer care, they rarely associate it with what goes on behind the scenes to create life-saving treatments. For starters, developing cell and gene therapies is pricey, and maintaining the manufacturing technology and environment is equally challenging. Supervising the minutiae of the machinery that fuels the Therapeutic Products Program (TPP) at Fred Hutch falls to Folashade “Shade” Otegbeye, MBChB, MPH. “Part of what we want to do is innovate processes in a way that recognizes the regulations and quality standards that govern the products we administer,” said Otegbeye. “We want to make sure we keep up with innovation and can rapidly translate what researchers are doing in the lab to the bedside." Otegbeye will get an assist in her efforts to innovate as the new holder of the Fleischauer Family Endowed Chair in Cell and Gene Therapy Translation. Read more: https://xmrrwallet.com/cmx.pbit.ly/3U4dpZt

At Fred Hutch, researchers are encouraged to explore new ideas and collaborate with one another. “Remember, the vast majority of advanced cancers are still not cured,” says Thomas J. Lynch Jr., MD, president and director of Fred Hutch and holder of the Raisbeck Endowed Chair. “And that problem is not an engineering problem. It’s an ideas problem. We need to continue to invest in basic science to be able to drive ideas that give us new opportunities to improve cures.” Groundbreaking research efforts from the Women’s Health Initiative to the Transformative Rare Cancer Initiative represent just two of the many research initiatives and programs Fred Hutch leads that are driving progress across a broad spectrum of diseases. Read more from the The Seattle Times: https://xmrrwallet.com/cmx.pbit.ly/46wFHTP

At first glance, art and science might seem like opposite worlds — one driven by imagination and emotion, the other by data and precision — but at their core, both seek to explore and explain the world around us. When these two fields intersect, they spark creativity, deepen understanding and invite new ways of interpreting ideas. Two years in the making, SxAffold is a new initiative designed to spark meaningful collaboration between scientists and artists. In early June, the program, sponsored by Brotman Baty Institute, launched its inaugural cohort — six artists working across various media — who came together for a fully funded, week-long workshop at Fred Hutch. "The main thing I’m really excited about with SxAffold and other projects that bring together science and art is the idea that we can reconstruct and redefine how scientists and artists might interact," said SxAffold organizer and Fred Hutch assistant professor Nasa Sinnott-Armstrong, PhD. Read more: https://xmrrwallet.com/cmx.pbit.ly/3UIiOpc