Psychostimulant drugs for cocaine dependence

X Castells, R Cunill, C Pérez‐Mañá… - Cochrane Database …, 2016 - cochranelibrary.com
X Castells, R Cunill, C Pérez‐Mañá, X Vidal, D Capellà
Cochrane Database of Systematic Reviews, 2016cochranelibrary.com
Background Cocaine dependence is a severe disorder for which no medication has been
approved. Like opioids for heroin dependence, replacement therapy with psychostimulants
could be an effective therapy for treatment. Objectives To assess the effects of
psychostimulants for cocaine abuse and dependence. Specific outcomes include sustained
cocaine abstinence and retention in treatment. We also studied the influence of type of drug
and comorbid disorders on psychostimulant efficacy.
Background
Cocaine dependence is a severe disorder for which no medication has been approved. Like opioids for heroin dependence, replacement therapy with psychostimulants could be an effective therapy for treatment.
Objectives
To assess the effects of psychostimulants for cocaine abuse and dependence. Specific outcomes include sustained cocaine abstinence and retention in treatment. We also studied the influence of type of drug and comorbid disorders on psychostimulant efficacy.
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