Welcome back to the Future of Health, where we look at the latest advances in the science of living and staying well. This time, we’re getting into which factors affect your personal risk from drinking alcohol, new hope for both PCOS and Chronic Lyme patients, science-backed tips for managing seasonal allergies, and more. This email has been medically reviewed by my colleague Dr. David Dodick.


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🔍 Now, here’s your dive into what has us intrigued and optimistic.


Be well,

Siobhan OConnor

Chief Content Officer, Atria

How to think about drinking alcohol


Nearly everywhere you look there are signs that people are rethinking their drinking. From the rise of sober-curious young people to the former United States Surgeon General’s advisory linking alcohol to cancer, the conversation around drinking is shifting rapidly. 


In the U.S., national guidelines currently recommend no more than two drinks per day for men and one drink per day for women. Those Dietary Guidelines for Americans are up for renewal this year, and after two large studies offered two very different visions for federal regulators to consider, recent reporting indicates the government is considering eliminating recommended limits altogether. 


Before we get into what the science says, it’s worth noting advocates on all sides have questioned the scientific basis for the current guidelines, with some experts arguing they reflect political compromises more than current research. Some researchers say the guidelines should be more strict, pointing out that one-size-fits-all recommendations fail to account for individual differences in genetic risk, metabolism, body composition, and health status. They also often rely on outdated gender binaries. Others, including alcohol industry advocates, have argued against tightening the guidelines at all.


With so much information swirling, it can be tough to make sense of what it means for you. Here’s how to think about alcohol and your health.


The back and forth from public health officials

The World Health Organization has said in recent years that there is no completely safe level of alcohol, and several countries, including Canada, the United Kingdom, and the Netherlands, have adopted similar messages, putting out guidelines that tighten the recommended limit of drinks. Next year, Ireland will become the first country in the world to introduce elaborate health warning labels on all alcohol products. Other recent research has found that alcohol is one of the key modifiable risk factors for dementia


This is a notable shift from previous health guidance suggesting that drinking in moderation could be beneficial. While the idea that a glass of wine with dinner was good for cardiovascular health was popular for decades, it has been largely debunked in recent years.


Some experts are concerned the current debate in the U.S. will confuse consumers. Consider that one of the two reports being considered by the federal government revived the idea that moderate drinking is linked to lower risk of heart disease and death from any cause. The other report says any amount of alcohol comes with health risks. For now, Atria experts recommend speaking with your own doctor rather than awaiting new national guidelines—or trying to parse the back and forth in the headlines.


Understanding your personal risk

While it makes sense for governments to release population health guidelines, Dr. David Dodick, a leading preventive neurologist and Chief Science and Medical Officer at the Atria Health and Research Institute, says your individual risk varies depending on many factors, including age, sex, and preexisting conditions, such as heart disease, neurological issues, liver disease, diabetes, and mental health issues. Your genetics also play a role: genes can influence how you metabolize alcohol as well as your risk of cancer, dementia, and other diseases. Even moderate alcohol consumption in people with certain genetic variants is associated with a significantly elevated risk of gastrointestinal tract cancers, brain atrophy (shrinkage), and cognitive decline. 


This is the kind of information that genomic sequencing can provide insight into. For those of us who have not done genetic testing, Dr. Dodick recommends considering a few factors: personal history of cancer, family history of cancer, neurodegenerative, and dementia disorders like Alzheimer’s; diet, sleep, and exercise routine; and any current conditions such as obesity, diabetes, hypertension, and heart disease.


“In individuals with underlying health conditions or at significant risk for future conditions, alcohol may act as a biological amplifier, accelerating disease onset and progression, intensifying symptoms, and undermining treatment. In other words, alcohol doesn't just add to the problem, it turns up the volume on whatever health issue you already have or are at risk for,” Dr. Dodick says. By contrast, for adults in good health who eat and sleep well and stay active, and who don't have significant genetic risk or conditions that increase alcohol-related risk, having a drink now and then is considered low risk based on the latest research.


Finding a balance

We know many of our individual behaviors, from sitting at work all day to eating cheeseburgers, may not be optimal for our health, and gleaning knowledge about why that’s the case can motivate us to make different choices.


“As a physician, I can sit here and say you should never smoke—but it took us over a century for medical consensus and public awareness to solidify into the never-smoke message,” Dr. Dodick says. “The key is helping people understand their individual risks.” 


There’s evidence education works. A new survey by the Annenberg Center for Public Policy at the University of Pennsylvania found that awareness of the link between alcohol and elevated cancer risk increased from 40% to 56% after the Surgeon General’s warning in January. Nearly 1 in 3 respondents said this information would make them less likely to accept a drink in a social situation.


It’s clear things are changing.


If you’re looking to slow down on drinking in the meantime, there are plenty of steps you can incorporate into your current social life. Here are a few examples from our colleagues: 

  • Try a mocktail, a non-alcoholic beer, or mix non-alcoholic herbal bitters into sparkling water—all tasty alternatives to alcohol and a nice ritual for some.
  • Create alcohol-free rituals with enjoyable alternatives such as fancy tea, adaptogenic elixirs, or creative hobbies. These can disrupt the reward loop from alcohol and find other ways to get pleasure.
  • Track your drinking. Use an app such as DrinkControl, Reframe, TryDry, or use a journal to monitor when, where, why, and how much you drink. This can help increase awareness and accountability. 
  • Set specific, achievable goals such as no alcohol on weekdays, no more than two drinks per week, or one drink at social events only. Gradual reduction is often more sustainable than abrupt abstinence. 
  • If you prefer a more subtle tactic at social events, a glass of seltzer with lime removes the alcohol—and the questions.


Ultimately, the decision to drink or not remains personal—and, as Dr. Dodick says, should be personalized. —Abigail Abrams


What we’re reading


  • Doctors in the U.K. announced that eight healthy babies have been born after procedures that combined the DNA of three people to create embryos, a technique designed to prevent children from being born with rare but fatal diseases caused by mutations in mitochondria. The U.K. first allowed the procedure, dubbed “three-parent IVF,” in 2015 and the long-awaited results raise many questions about how genetic technologies will be used in the future.

  • Some women with polycystic ovary syndrome (PCOS) are reporting improvements in symptoms after using GLP-1 medications, according to this CNBC story. This is one of several unapproved but potentially important uses of the drugs beyond treating diabetes and weight-loss. PCOS is often underdiagnosed and does not have a standard treatment, though more research is needed to understand why GLP-1s may ease PCOS symptoms.


  • Is all this salt killing us? That’s the question Grubstreet asks in this article examining how many restaurants deliver the recommended max of 1,500 mg of salt per day in a single meal.


  • Chronic Lyme, long dismissed as psychosomatic or worse, is finally getting more attention and research funding, reports the Wall Street Journal. Newer trials are starting to track Lyme patients and investigate potential treatments. As one researcher said: “I want to find a way to give people hope.” 
1 in 6

Number of the Week


The proportion of adults with hypertension unaware they have the condition, according to a study of 15,300 U.S. adults with cardiovascular risk factors. This rose significantly from 2013 to 2023, suggesting the COVID-19 pandemic may have disrupted care and highlighting the need for preventive screenings.


JAMA Cardiology

Lifestyle interventions for managing seasonal allergies


Seasonal allergies aren’t just annoying—they’re an immune system rebellion that leaves an increasing number of people trapped in a cycle of sneezing, itching, and brain fog. While over-the-counter antihistamines are generally considered safe and can be effective for most people, it’s also useful to look at the underlying causes of allergies, including inflammation, says Robert Kachko, ND, LAc, a top naturopathic physician and Atria Director of Integrative Health.


There are various techniques that can bring relief and help you spend time outside during allergy season.


Lifestyle factors

  • Maintaining a balanced diet of anti-inflammatory foods supports your immune system.
  • Staying well-hydrated helps thin mucus secretions and supports respiratory function.
  • Try consuming local raw honey, which may help build tolerance to local pollen.
  • Getting adequate sleep supports immune function and managing inflammatory responses.
  • Nasal irrigation with a neti pot can effectively flush out pollen, dust, and other irritants.


Home environment strategies

  • Air filtration: Air purifiers rated for allergies, ideally with a HEPA filter, can reduce allergens. If you have an HVAC system, experts recommend upgrading to at least a MERV 11 filter.
  • Reduce indoor allergen exposure by removing shoes at the door, changing clothes after spending extended periods outside, and showering before bed.


Supplements and natural approaches

Though not a comprehensive solution on their own, certain supplements may provide additional relief for seasonal allergy sufferers.

  • Quercetin is a natural mast cell stabilizer that may reduce allergic reactions.
  • Stinging nettle leaf has demonstrated anti-inflammatory properties.
  • Vitamin C offers mild antihistamine properties.

As with any supplement regimen, consult with a health care provider before starting anything new, especially if you take other medications. Take a look at more allergy advice in the full article on our website.

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